The thinning of the bones including the reduction in bone mass because of the depletion of calcium and bone protein.

Osteoporosis easily results in fractures of the bones, which are often slow to heal and then even heal poorly.

It is more common in older adults, particularly post-menopausal women; in patients on steroids; and in those who take steroidal drugs.

Unchecked osteoporosis can lead to changes in posture, physical abnormality; especially, a form of hunch back expressed by some people as "dowager's hump", and a decreased ability to move around.